Event-related potentials to task-irrelevant sad faces as a state marker of depression
Year of publication
2020
Authors
Ruohonen, Elisa M.; Alhainen, Veera; Astikainen, Piia
Abstract
Negative bias in face processing has been demonstrated in depression, but there are no longitudinal investigations of negative bias in symptom reduction. We recorded event-related potentials (P1 and N170) to task-irrelevant facial expressions in depressed participants who were later provided with a psychological intervention and in never depressed control participants. Follow-up measurements were conducted for the depressed group two and 39 months later. Negative bias was found specifically in the depression group, and was demonstrated as enlarged P1 amplitude to sad faces, which normalized in the follow-up measurements when the participants had fewer symptoms. Because the P1 amplitude recorded at the baseline did not differ between the depression group that recovered and the group that did not recover after the intervention, this brain response did not show potential as a biomarker for treatment response. It could have potential, however, to serve as a state-marker of depression.
Show moreOrganizations and authors
Publication type
Publication format
Article
Parent publication type
Journal
Article type
Original article
Audience
ScientificPeer-reviewed
Peer-ReviewedMINEDU's publication type classification code
A1 Journal article (refereed), original researchPublication channel information
Journal
Publisher
Volume
149
Article number
107806
ISSN
Publication forum
Publication forum level
2
Open access
Open access in the publisher’s service
No
Self-archived
Yes
Other information
Fields of science
Psychology
Keywords
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Publication country
Netherlands
Internationality of the publisher
International
Language
English
International co-publication
No
Co-publication with a company
No
DOI
10.1016/j.biopsycho.2019.107806
The publication is included in the Ministry of Education and Culture’s Publication data collection
Yes