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Publications information icon

Discovery of compounds inhibiting the ADP-ribosyltransferase activity of pertussis toxin

Peer-reviewed
Open access
DOI
10.1021/acsinfecdis.9b00412
Ashok, Yashwanth; Miettinen, Moona; de Oliveira, Danilo Kimio Hirabae; Tamirat, Mahlet Z.; Näreoja, ...
ACS infectious diseases2020Publications information icon

ADP-ribosylation in DNA repair – structural studies of human ADP-ribosyltransferase 2

Obaji, Ezeogo Ogbonnaya
Faculty of biochemisty and molecular medicine2018Publications information icon

The zinc-binding motif in tankyrases is required for the structural integrity of the catalytic ADP-ribosyltransferase domain

Peer-reviewed
Open access
DOI
10.1098/rsob.210365
Sowa, Sven T.; Lehtiö, Lari
Open biology2022Publications information icon

Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10

Peer-reviewed
Open access
DOI
10.1002/open.202100087
Korn, Patricia; Classen, Arno; Murthy, Sudarshan; Guareschi, Riccardo; Maksimainen, Mirko M.; Lippok...
ChemistryOpen2021Publications information icon

4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10

Peer-reviewed
Open access
DOI
10.1016/j.ejmech.2018.06.047
Murthy, Sudarshan; Desantis, Jenny; Verheugd, Patricia; Maksimainen, Mirko M.; Venkannagari, Harikan...
European journal of medicinal chemistry2018Publications information icon

Small-molecule screening assay for mono-adp-ribosyltransferases

Peer-reviewed
Open access
DOI
10.1007/978-1-4939-8588-3_16
Haikarainen, Teemu; Murthy, Sudarshan; Maksimainen, Mirko; Lehtiö, Lari
Methods in molecular biology2018Publications information icon

Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs

Peer-reviewed
Open access
DOI
10.1016/j.bmc.2021.116511
Maksimainen, Mirko M.; Murthy, Sudarshan; Sowa, Sven T.; Galera Prat, Albert; Rolina, Elena; Heiskan...
Bioorganic and medicinal chemistry2021Publications information icon

Assay technologies facilitating drug discovery for ADP-ribosyl writers, readers and erasers

Peer-reviewed
Open access
DOI
10.1002/bies.202100240
Glumoff, Tuomo; Sowa, Sven T.; Lehtiö, Lari
Bioessays2022Publications information icon

ADP-ribosyltransferases, an update on function and nomenclature

Peer-reviewed
Open access
DOI
10.1111/febs.16142
Lüscher, B.; Ahel, I.; Altmeyer, M.; Ashworth, A.; Bai, P.; Chang, P.; Cohen, M.; Corda, D.; Dantzer...
Febs journal2021Publications information icon

Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage

Peer-reviewed
Open access
DOI
10.1016/j.chembiol.2016.08.012
Venkannagari, Harikanth; Verheugd, Patricia; Koivunen, Jarkko; Haikarainen, Teemu; Obaji, Ezeogo; ...
Cell Chemical Biology2016

Discovery of compounds inhibiting the ADP-ribosyltransferase activity of pertussis toxin

Peer-reviewed
Open access
DOI
10.1021/acsinfecdis.9b00412
2020

ADP-ribosylation in DNA repair – structural studies of human ADP-ribosyltransferase 2

2018

The zinc-binding motif in tankyrases is required for the structural integrity of the catalytic ADP-ribosyltransferase domain

Peer-reviewed
Open access
DOI
10.1098/rsob.210365
2022

Evaluation of 3- and 4-Phenoxybenzamides as Selective Inhibitors of the Mono-ADP-Ribosyltransferase PARP10

Peer-reviewed
Open access
DOI
10.1002/open.202100087
2021

4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10

Peer-reviewed
Open access
DOI
10.1016/j.ejmech.2018.06.047
2018

Small-molecule screening assay for mono-adp-ribosyltransferases

Peer-reviewed
Open access
DOI
10.1007/978-1-4939-8588-3_16
2018

Analogs of TIQ-A as inhibitors of human mono-ADP-ribosylating PARPs

Peer-reviewed
Open access
DOI
10.1016/j.bmc.2021.116511
2021

Assay technologies facilitating drug discovery for ADP-ribosyl writers, readers and erasers

Peer-reviewed
Open access
DOI
10.1002/bies.202100240
2022

ADP-ribosyltransferases, an update on function and nomenclature

Peer-reviewed
Open access
DOI
10.1111/febs.16142
2021

Small-Molecule Chemical Probe Rescues Cells from Mono-ADP-Ribosyltransferase ARTD10/PARP10-Induced Apoptosis and Sensitizes Cancer Cells to DNA Damage

Peer-reviewed
Open access
DOI
10.1016/j.chembiol.2016.08.012
2016