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Publications information icon

Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling

Peer-reviewed
Open access
DOI
10.3390/cancers13040927
Siddiqui, Farid Ahmad; Parkkola, Hanna; Vukic, Vladimir; Oetken-Lindholm, Christina; Jaiswal, Alok; ...
Cancers2021Publications information icon

HSP90 expression is associated with outcome in pulmonary carcinoid tumor patients

Peer-reviewed
Open access
DOI
10.21037/tlcr-23-304
Niinimäki, Jenni; Sihto, Harri; Arola, Johanna; Vesterinen, Tiina
Translational lung cancer research2023Publications information icon

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

Peer-reviewed
Open access
DOI
10.1038/s41598-018-25404-w
Kijima Toshiki; Prince Thomas L.; Tigue Megan L.; Yim Kendrick H.; Schwartz Harvey; Beebe Kristin; L...
Scientific Reports2018Publications information icon

New, Non-quinone Fluorogeldanamycin Derivatives Strongly Inhibit Hsp90

Peer-reviewed
DOI
10.1002/cbic.201402375
Hermane Jekaterina, Bulyszko Ilona, Eichner Simone, Sasse Florenz, Collisi Wera, Poso Antti, Schax E...
CHEMBIOCHEM : A EUROPEAN JOURNAL OF CHEMICAL BIOLOGY2015Publications information icon

Inhibition of Hepatitis C replication by targeting the molecular chaperone Hsp90 - synthesis and biological evaluation of 4,5,6,7-tetrahydrobenzo[1,2-d]thiazole derivatives

Peer-reviewed
Open access
DOI
10.1002/cmdc.201800724
Lillsunde, Katja-Emilia M; Tomašič, Tihomir; Schult, Philipp; Lohmann, Volker; Kikelj, Danijel; Tamm...
ChemMedChem : chemistry enabling drug discovery.2019Publications information icon

Marine alkaloid oroidin analogues with antiviral potential: a novel class of synthetic compounds targeting the cellular chaperone Hsp90

Peer-reviewed
Open access
DOI
10.1111/cbdd.13034
Lillsunde, Katja-Emilia ; Tomašič, Tihomir; Kikelj, Danijel; Tammela, Päivi
Chemical Biology and Drug Design (Print)2017Publications information icon

Revealing the interaction mode of the highly flexible Sorghum bicolor Hsp70/Hsp90 organizing protein (Hop): A conserved carboxylate clamp confers high affinity binding to Hsp90.

Peer-reviewed
DOI
10.1016/j.jprot.2018.02.007
R Adão; LM Zanphorlin; TB Lima; D Sriranganadane; Käthe Dahlström; Pinheiro GMS; FC Gozzo; Barbosa L...
Journal of Proteomics2019Publications information icon

TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

Peer-reviewed
Open access
DOI
10.3390/ijms22094875
Ranta-aho, Sofia; Piippo, Niina; Korhonen, Eveliina; Kaarniranta, Kai; Hytti, Maria; Kauppinen, Anu
International journal of molecular sciences2021Publications information icon

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

Peer-reviewed
Piippo N; Korhonen E; Hytti M; Skottman H; Kinnunen K; Josifovska N; Petrovski G; Kaarniranta K; Kau...
Scientific Reports2018Publications information icon

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

Peer-reviewed
Open access
DOI
10.1038/s41598-018-25123-2
Piippo, Niina;Korhonen, Eveliina;Hytti, Maria;Skottman, Heli;Kinnunen, Kati;Josifovska, Natasha;Gora...
scientific reports2018

Novel Small Molecule Hsp90/Cdc37 Interface Inhibitors Indirectly Target K-Ras-Signaling

Peer-reviewed
Open access
DOI
10.3390/cancers13040927
2021

HSP90 expression is associated with outcome in pulmonary carcinoid tumor patients

Peer-reviewed
Open access
DOI
10.21037/tlcr-23-304
2023

HSP90 inhibitors disrupt a transient HSP90-HSF1 interaction and identify a noncanonical model of HSP90-mediated HSF1 regulation

Peer-reviewed
Open access
DOI
10.1038/s41598-018-25404-w
2018

New, Non-quinone Fluorogeldanamycin Derivatives Strongly Inhibit Hsp90

Peer-reviewed
DOI
10.1002/cbic.201402375
2015

Inhibition of Hepatitis C replication by targeting the molecular chaperone Hsp90 - synthesis and biological evaluation of 4,5,6,7-tetrahydrobenzo[1,2-d]thiazole derivatives

Peer-reviewed
Open access
DOI
10.1002/cmdc.201800724
2019

Marine alkaloid oroidin analogues with antiviral potential: a novel class of synthetic compounds targeting the cellular chaperone Hsp90

Peer-reviewed
Open access
DOI
10.1111/cbdd.13034
2017

Revealing the interaction mode of the highly flexible Sorghum bicolor Hsp70/Hsp90 organizing protein (Hop): A conserved carboxylate clamp confers high affinity binding to Hsp90.

Peer-reviewed
DOI
10.1016/j.jprot.2018.02.007
2019

TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells

Peer-reviewed
Open access
DOI
10.3390/ijms22094875
2021

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

Peer-reviewed
2018

Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome

Peer-reviewed
Open access
DOI
10.1038/s41598-018-25123-2
2018