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Latest advances in aging research and drug discovery

Peer-reviewed
Open access
DOI
10.18632/aging.102487
Bakula, Daniela; Ablasser, Andrea; Aguzzi, Adriano; Antebi, Adam; Barzilai, Nir; Bittner, Martin-Imm...
Aging2019

Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging

Peer-reviewed
Open access
DOI
10.1038/s43587-021-00159-8
FinnGen; BioBank Japan Project; Timmers, Paul R. H. J.; Tiys, Evgeny S.; Sakaue, Saori; Akiyama, Mas...
Nature Aging2022

Early vascular aging ambulatory score in acute ischemic stroke

Peer-reviewed
Open access
DOI
10.1038/s41514-025-00202-7
Kakaletsis, Nikolaos; Kotsis, Vasilios; Hosomi, Naohisa; Nezu, Tomohisa; Michel, Patrik; Guillaume, ...
npj aging2025

Biological Aging Acceleration in Major Depressive Disorder:A Multi-Omics Analysis

Peer-reviewed
Open access
DOI
10.1111/acel.70310
Diniz, Breno Satler; Zhao, Shangshu; Drouard, Gabin; Vuoksimaa, Eero; Ollikainen, Miina; Lenze, Eric...
Aging Cell2026

Aging disrupts MANF-mediated immune modulation during skeletal muscle regeneration

Peer-reviewed
Open access
DOI
10.1038/s43587-023-00382-5
Sousa, Neuza S.; Bras, Margarida F.; Antunes, Ines B.; Lindholm, Paivi; Neves, Joana; Sousa-Victor, ...
Nature Aging2023

First Direct Evidence of Accelerated Molecular Aging in Intracranial Aneurysmal Tissue

Peer-reviewed
Open access
DOI
10.1111/acel.70231
Khan, Dilaware; Li, Xuanchen; Hewera, Michael; Muhammad, Sajjad
Aging cell2025

Medin amyloid may drive arterial aging and disease in the periphery and brain

Peer-reviewed
DOI
10.1038/s43587-023-00481-3
Madine, Jillian; Davies, Hannah A.; Migrino, Raymond Q.; Ruotsalainen, Sanni E.; Wagner, Jessica; Ne...
Nature Aging2023

Associations Between 40-Year Trajectories of BMI and Proteomic and Epigenetic Aging Clocks:Deciphering Nonlinearity and Interactions

Peer-reviewed
Open access
DOI
10.1111/acel.70397
Drouard, Gabin; Argentieri, M. Austin; Heikkinen, Aino; Ollikainen, Miina; Kaprio, Jaakko
Aging Cell2026

Studying constructions of aging manhood::Methodological considerations

Peer-reviewed
DOI
10.1016/j.jaging.2022.101050
Calasanti, Toni; Pietilä, Ilkka; King, Neal; Ojala, Hanna
Journal of aging studies2022

Deep learning-based prediction of one-year mortality in Finland is an accurate but unfair aging marker

Peer-reviewed
Open access
DOI
10.1038/s43587-024-00657-5
Vabalas, Andrius; Hartonen, Tuomo; Vartiainen, Pekka; Jukarainen, Sakari; Viippola, Essi; Rodostheno...
Nature aging2024

Latest advances in aging research and drug discovery

Peer-reviewed
Open access
DOI
10.18632/aging.102487
2019

Mendelian randomization of genetically independent aging phenotypes identifies LPA and VCAM1 as biological targets for human aging

Peer-reviewed
Open access
DOI
10.1038/s43587-021-00159-8
2022

Early vascular aging ambulatory score in acute ischemic stroke

Peer-reviewed
Open access
DOI
10.1038/s41514-025-00202-7
2025

Biological Aging Acceleration in Major Depressive Disorder:A Multi-Omics Analysis

Peer-reviewed
Open access
DOI
10.1111/acel.70310
2026

Aging disrupts MANF-mediated immune modulation during skeletal muscle regeneration

Peer-reviewed
Open access
DOI
10.1038/s43587-023-00382-5
2023

First Direct Evidence of Accelerated Molecular Aging in Intracranial Aneurysmal Tissue

Peer-reviewed
Open access
DOI
10.1111/acel.70231
2025

Medin amyloid may drive arterial aging and disease in the periphery and brain

Peer-reviewed
DOI
10.1038/s43587-023-00481-3
2023

Associations Between 40-Year Trajectories of BMI and Proteomic and Epigenetic Aging Clocks:Deciphering Nonlinearity and Interactions

Peer-reviewed
Open access
DOI
10.1111/acel.70397
2026

Studying constructions of aging manhood::Methodological considerations

Peer-reviewed
DOI
10.1016/j.jaging.2022.101050
2022

Deep learning-based prediction of one-year mortality in Finland is an accurate but unfair aging marker

Peer-reviewed
Open access
DOI
10.1038/s43587-024-00657-5
2024