Lipids are important structural and functional components of all living organisms. The composition and structure of lipids are the results of complex regulation of multiple biosynthesis pathways and determine the nutritional properties and physiological effects of fats and oils. Despite the importance of lipids, the detailed molecular structures of individual lipid molecules and the specific structure-function relationships remain largely unknown in most organisms. To fill the knowledge gap, this research aims to update the current knowledge on structures and functions of natural lipids. We will develop and apply novel methods to reveal the structures of lipid molecules in different organisms. Using human milk fat as an example, we will perform in-depth research on the structures of the fat molecules and their importance for infant nutrition. The research will improve the current understanding of lipid biochemistry as well as lipids in nutrition, health and diseases.

2023

2027