The prevalence of inflammatory bowel diseases (IBD) such as Crohn's disease (CD) is increasing in the adult population. The diagnosis for these diseases is demanding and there is an urgent need for more specific and faster diagnostic methods. Recent studies have demonstrated that positron emission tomography (PET) could be used effectively in the diagnostics of CD. In this study, we evaluate the use of different PET tracers in the preclinical IBD model. After the validation process in the preclinical model, the most accurate tracer will be used in the clinical imaging of patients with a suspicion of CD. This project will provide further understanding in the pathophysiology of IBD and on the methods for more accurate and faster diagnosis in the field of IBD.

2022

2026