In this project, we will investigate how targeted therapy in lung cancer influence the tumor immune response. Cancer cells that change during treatment may affect the tumor immune response. This could have a significant impact on treatment efficacy and the development of resistance. The project utilizes new mouse models and advanced single-cell techniques to comprehensively investigate the targeted therapy -induced changes in the tumor immune response in lung cancer, and to understand in detail the role of treatment-altered cancer cells in regulating the immune response. Our ultimate goal is to develop and test new ways to treat lung cancer.

2025

2029