Dupuytren's contracture is common hereditary hand disorder, marked by fibrous cords in hands and fingers limiting daily activities of middle age and elderly people. Our study delves into effectiveness of three commonly used treatments: surgery, needle fasciotomy (breaking the cord without wounds under local anaesthesia), and collagenase injection (drug injection). We've enlisted 302 participants across six Finnish centres, and will evaluate effectiveness of treatments and costs over 10 years. Our methods include patient interviews, comprehensive assessment of hand function, and patient satisfaction to treatment outcomes. Using statistical analyses, we will estimate the differences in the effects and costs between the treatments when applied widely in clinical practice. The trial is independent researcher-led study that aims to offer reliable evidence-based information for patients and healthcare workers and help optimising utilisation of healthcare resources.

2025

2029