Development of synthetic biology tools for biomedicine.

Description of the granted funding

Our research project focuses on developing innovative cancer treatments using synthetic biology. We aim to address the urgent need for more effective therapies. We will create two research platforms: nanobodies that effectively target and mark cancer cells for immune system attack, and light-controllable molecular tools for the precise regulation of cancer cell genes, thereby reducing tumor growth and enhancing the immune response against cancer. Our methods include protein engineering, cell culture experiments, and studies using humanized animal models to assess our approaches. Conducted at the Faculty of Medicine at the University of Helsinki, this research aims to develop cancer treatments with enhanced efficacy and reduced side effects, improving patient outcomes and alleviating the burden of cancer treatment. By showcasing the potential of synthetic biology, we seek to develop smarter, safer therapies that can transform treatment paradigms and advance biomedicine.
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Starting year

2026

End year

2031

Granted funding

Vladislav Verkhusha Orcid -palvelun logo
2 398 842 €

Funder

Research Council of Finland

Funding instrument

Academy Professors

Decision maker

Suomen akatemian muu päättäjä
29.10.2025

Other information

Funding decision number

369710

Fields of science

Biochemistry, cell and molecular biology

Research fields

Biokemia, biofysiikka

Identified topics

cancer