This proposal aims to develop a system for the prospective real-time reporting of clinically meaningful molecular findings, extracted from cancer patients' research profiling data using the integrative molecular tumor board (iMTB) tool and returned to the clinics via biobank. The iMTB tool and process development takes advantage of the data in iCAN Digital Precision Cancer Medicine Flagship project (www.ican.fi), where each patient's longitudinal health information is combined with molecular profiling data in a secure analysis platform. This project develops iMTB modules for omics and cohort analysis as well as focuses on automation and secure data return of the reports. In addition, we aim to integrate iMTB into hospital electronic health record system to systematically discover and utilize biomarkers of diagnostic, prognostic and therapeutic significance for the benefit of cancer patients.

2026

2028