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In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2019.105118
Juvonen, Risto O.; Heikkinen, Aki T.; Kärkkäinen, Olli; Jehangir, Rabia; Huuskonen, Juhani; Troberg,...
European journal of pharmaceutical sciences2020

Drug glucuronidation assays on human liver microsomes immobilized on microfluidic flow-through reactors

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2020.105677
Kiiski, Iiro; Ollikainen, Elisa; Artes, Sanna; Järvinen, Päivi; Jokinen, Ville; Sikanen, Tiina
European journal of pharmaceutical sciences2021

Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes

Peer-reviewed
DOI
10.1016/j.ejps.2010.12.002
Hokkanen Juho, Tolonen A, Mattila Sampo, Turpeinen Miia
European journal of pharmaceutical sciences2011

Characterization of furathiocarb metabolism in in-vitro human liver microsomes and recombinant cytochrome P450 enzymes

Peer-reviewed
Open access
DOI
10.1016/j.toxrep.2022.03.046
Abass, Khaled; Reponen, Petri; Alsanie, Walaa F.; Rautio, Arja; Pelkonen, Olavi
Toxicology reports2022

Cytochrome P450 Inhibition by Antimicrobials and Their Mixtures in Rainbow Trout Liver Microsomes In Vitro

Peer-reviewed
Open access
DOI
10.1002/etc.5160
Pihlaja, Tea L. M.; Niemissalo, Sanna M.; Sikanen, Tiina M.
Environmental Toxicology and Chemistry2022

Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases

Peer-reviewed
DOI
10.1124/jpet.111.184721
Bratton, Stacie M.; Mosher, Carrie M.; Khallouki, Farid; Finel, Moshe; Court, Michael H.; Moran, Jef...
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS2012

The impact of porous silicon nanoparticles on human cytochrome P450 metabolism in human liver microsomes in vitro

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2017.03.039
Ollikainen, Elisa ; Liu, Dongfei; Kallio, Arttu; Mäkilä, Ermei ; Zhang, Hongbo; Salonen, Jarno; Alme...
European journal of pharmaceutical sciences2017

Formation of GSH-trapped reactive metabolites in human liver microsomes, S9 fraction, HepaRG-cells, and human hepatocytes

Peer-reviewed
DOI
10.1016/j.jpba.2015.07.020
Lassila, Toni; Rousu, Timo; Mattila, Sampo; Chesne, Christophe; Pelkonen, Olavi; Turpeinen, Miia; To...
Journal of pharmaceutical and biomedical analysis2015

Formation of GSH-trapped reactive metabolites in human liver microsomes, S9 fraction, HepaRG-cells, and human hepatocytes

Peer-reviewed
Lassila T; Rousu T; Mattila S; Chesné C; Pelkonen O; Turpeinen M; Tolonen A
Journal of Pharmaceutical And Biomedical Analysis2015

Identification of metabolites of fosinopril produced by human and rat liver microsomes with liquid chromatography-mass spectrometry

Peer-reviewed
DOI
10.1016/j.ejps.2013.12.009
Uutela, Paivi; Monto, Matti; Iso-Mustajarvi, Ilona; Madetoja, Mari; Yliperttula, Marjo; Ketola, Raim...
European journal of pharmaceutical sciences2014

In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2019.105118
2020

Drug glucuronidation assays on human liver microsomes immobilized on microfluidic flow-through reactors

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2020.105677
2021

Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes

Peer-reviewed
DOI
10.1016/j.ejps.2010.12.002
2011

Characterization of furathiocarb metabolism in in-vitro human liver microsomes and recombinant cytochrome P450 enzymes

Peer-reviewed
Open access
DOI
10.1016/j.toxrep.2022.03.046
2022

Cytochrome P450 Inhibition by Antimicrobials and Their Mixtures in Rainbow Trout Liver Microsomes In Vitro

Peer-reviewed
Open access
DOI
10.1002/etc.5160
2022

Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases

Peer-reviewed
DOI
10.1124/jpet.111.184721
2012

The impact of porous silicon nanoparticles on human cytochrome P450 metabolism in human liver microsomes in vitro

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2017.03.039
2017

Formation of GSH-trapped reactive metabolites in human liver microsomes, S9 fraction, HepaRG-cells, and human hepatocytes

Peer-reviewed
DOI
10.1016/j.jpba.2015.07.020
2015

Formation of GSH-trapped reactive metabolites in human liver microsomes, S9 fraction, HepaRG-cells, and human hepatocytes

Peer-reviewed
2015

Identification of metabolites of fosinopril produced by human and rat liver microsomes with liquid chromatography-mass spectrometry

Peer-reviewed
DOI
10.1016/j.ejps.2013.12.009
2014