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Drug glucuronidation assays on human liver microsomes immobilized on microfluidic flow-through reactors

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2020.105677
Kiiski, Iiro; Ollikainen, Elisa; Artes, Sanna; Järvinen, Päivi; Jokinen, Ville; Sikanen, Tiina
European journal of pharmaceutical sciences2021

Metabolic profiling and in vitro-in vivo extrapolation of furathiocarb in mammalian hepatic microsomes

Peer-reviewed
Open access
DOI
10.1016/j.toxrep.2022.03.030
Abass, Khaled; Reponen, Petri; Alsanie, Walaa F.; Rautio, Arja; Pelkonen, Olavi
Toxicology reports2022

Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes

Peer-reviewed
DOI
10.1016/j.ejps.2010.12.002
Hokkanen Juho, Tolonen A, Mattila Sampo, Turpeinen Miia
European journal of pharmaceutical sciences2011

Evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes

Peer-reviewed
DOI
10.1080/03601230902997766
Abass K, Turpeinen M, Pelkonen O
Journal of Environmental Science and Health Part B2009

Cytochrome P450 Inhibition by Antimicrobials and Their Mixtures in Rainbow Trout Liver Microsomes In Vitro

Peer-reviewed
Open access
DOI
10.1002/etc.5160
Pihlaja, Tea L. M.; Niemissalo, Sanna M.; Sikanen, Tiina M.
Environmental Toxicology and Chemistry2022

Characterization of furathiocarb metabolism in in-vitro human liver microsomes and recombinant cytochrome P450 enzymes

Peer-reviewed
Open access
DOI
10.1016/j.toxrep.2022.03.046
Abass, Khaled; Reponen, Petri; Alsanie, Walaa F.; Rautio, Arja; Pelkonen, Olavi
Toxicology reports2022

In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2019.105118
Juvonen, Risto O.; Heikkinen, Aki T.; Kärkkäinen, Olli; Jehangir, Rabia; Huuskonen, Juhani; Troberg,...
European journal of pharmaceutical sciences2020

Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases

Peer-reviewed
DOI
10.1124/jpet.111.184721
Bratton, Stacie M.; Mosher, Carrie M.; Khallouki, Farid; Finel, Moshe; Court, Michael H.; Moran, Jef...
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS2012

The impact of porous silicon nanoparticles on human cytochrome P450 metabolism in human liver microsomes in vitro

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2017.03.039
Ollikainen, Elisa ; Liu, Dongfei; Kallio, Arttu; Mäkilä, Ermei ; Zhang, Hongbo; Salonen, Jarno; Alme...
European journal of pharmaceutical sciences2017

An investigation into the formation of tebufenozide's toxic aromatic amine metabolites in human in vitro hepatic microsomes

Peer-reviewed
Open access
DOI
10.1016/j.pestbp.2016.03.001
Abass, Khaled M.
Pesticide biochemistry and physiology2016

Drug glucuronidation assays on human liver microsomes immobilized on microfluidic flow-through reactors

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2020.105677
2021

Metabolic profiling and in vitro-in vivo extrapolation of furathiocarb in mammalian hepatic microsomes

Peer-reviewed
Open access
DOI
10.1016/j.toxrep.2022.03.030
2022

Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes

Peer-reviewed
DOI
10.1016/j.ejps.2010.12.002
2011

Evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes

Peer-reviewed
DOI
10.1080/03601230902997766
2009

Cytochrome P450 Inhibition by Antimicrobials and Their Mixtures in Rainbow Trout Liver Microsomes In Vitro

Peer-reviewed
Open access
DOI
10.1002/etc.5160
2022

Characterization of furathiocarb metabolism in in-vitro human liver microsomes and recombinant cytochrome P450 enzymes

Peer-reviewed
Open access
DOI
10.1016/j.toxrep.2022.03.046
2022

In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2019.105118
2020

Analysis of R- and S-Hydroxywarfarin Glucuronidation Catalyzed by Human Liver Microsomes and Recombinant UDP-Glucuronosyltransferases

Peer-reviewed
DOI
10.1124/jpet.111.184721
2012

The impact of porous silicon nanoparticles on human cytochrome P450 metabolism in human liver microsomes in vitro

Peer-reviewed
Open access
DOI
10.1016/j.ejps.2017.03.039
2017

An investigation into the formation of tebufenozide's toxic aromatic amine metabolites in human in vitro hepatic microsomes

Peer-reviewed
Open access
DOI
10.1016/j.pestbp.2016.03.001
2016