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Mitoxantrone, pixantrone, and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-κB activation, and decrease TNF-alpha secretion in primary microglia

Peer-reviewed
DOI
10.1016/j.ejps.2020.105493
Rinne, Maiju Kaarina; Mätlik, Kert; Ahonen, Tiina Johanna; Vedovi, Fabio; Zappia, Giovanni; Moreira,...
European journal of pharmaceutical sciences2020

Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone

Peer-reviewed
DOI
10.1016/j.bbapap.2013.07.001
Ylilauri, Mikko; Mattila, Elina; Nurminen, Elisa M.; Käpylä, Jarmo; Niinivehmas, Sanna P.; Määttä, J...
Biochimica et Biophysica Acta: Proteins and Proteomics2013

Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.

Peer-reviewed
DOI
10.1016/j.bbapap.2013.07.001
Ylilauri Mikko; Mattila Elina; Nurminen Elisa M; Käpylä Jarmo; Niinivehmas Sanna P; Määttä Juha A;...
Biochimica et biophysica acta: international journal of biochemistry and biophysics2013

Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone

Peer-reviewed
Open access
DOI
10.1371/journal.pone.0105526
Alpay, Kemal; Farshchian, Mehdi; Tuomela, Johanna; Sandholm, Jouko; Aittokallio, Kaappo; Siljamäki, ...
PLoS ONE2014

Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone

Peer-reviewed
Alpay K; Farshchian M; Tuomela J; Sandholm J; Aittokallio K; Siljamäki E; Kallio M; Kähäri V-M; Hiet...
Plos One (electronic)2014

Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease

Peer-reviewed
DOI
10.1200/JCO.23.01841
Tierens, Anne; Arad-Cohen, Nira; Cheuk, Daniel; De Moerloose, Barbara; Fernandez Navarro, Jose Maria...
Journal of clinical oncology2024

Biweekly Cabazitaxel Is a Safe Treatment Option for Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients After Docetaxel - A Final Analysis of the Prosty II Trial

Peer-reviewed
Open access
DOI
10.21873/anticanres.14715
Kellokumpu-Lehtinen, Pirkko-Liisa;Kellokumpu-Lehtinen, Pirkko-Liisa;Kellokumpu-Lehtinen, Pirkko-Liis...
Anticancer research2020

Targeting DNA Homologous Repair Proficiency With Concomitant Topoisomerase II and c-Abl Inhibition

Peer-reviewed
Open access
DOI
10.3389/fonc.2021.733700
Siddiqui, Arafat; Tumiati, Manuela; Joko, Alia; Sandholm, Jouko; Roering, Pia; Aakko, Sofia; Vainion...
Frontiers in oncology2021

Multimodal Primary Treatment of Metastatic Prostate Cancer with Androgen Deprivation and Radiation

Peer-reviewed
DOI
10.21873/anticanres.11242
Joensuu, Timo; Joensuu , Greetta; Kairemo, Kalevi; Kiljunen, Timo; Riener, Maigo; Aaltonen, Aili; Al...
Anticancer research2016

MS-taudin ja sen lääkehoitojen vaikutus syöpäriskiin

Peer-reviewed
Open access
Atula, Sari; Laakso, Sini; Nevala, Riikka; Järvinen, Elina
Duodecim2022

Mitoxantrone, pixantrone, and mitoxantrone (2-hydroxyethyl)piperazine are toll-like receptor 4 antagonists, inhibit NF-κB activation, and decrease TNF-alpha secretion in primary microglia

Peer-reviewed
DOI
10.1016/j.ejps.2020.105493
2020

Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone

Peer-reviewed
DOI
10.1016/j.bbapap.2013.07.001
2013

Molecular mechanism of T-cell protein tyrosine phosphatase (TCPTP) activation by mitoxantrone.

Peer-reviewed
DOI
10.1016/j.bbapap.2013.07.001
2013

Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone

Peer-reviewed
Open access
DOI
10.1371/journal.pone.0105526
2014

Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone

Peer-reviewed
2014

Mitoxantrone Versus Liposomal Daunorubicin in Induction of Pediatric AML With Risk Stratification Based on Flow Cytometry Measurement of Residual Disease

Peer-reviewed
DOI
10.1200/JCO.23.01841
2024

Biweekly Cabazitaxel Is a Safe Treatment Option for Metastatic Castration-resistant Prostate Cancer (mCRPC) Patients After Docetaxel - A Final Analysis of the Prosty II Trial

Peer-reviewed
Open access
DOI
10.21873/anticanres.14715
2020

Targeting DNA Homologous Repair Proficiency With Concomitant Topoisomerase II and c-Abl Inhibition

Peer-reviewed
Open access
DOI
10.3389/fonc.2021.733700
2021

Multimodal Primary Treatment of Metastatic Prostate Cancer with Androgen Deprivation and Radiation

Peer-reviewed
DOI
10.21873/anticanres.11242
2016

MS-taudin ja sen lääkehoitojen vaikutus syöpäriskiin

Peer-reviewed
Open access
2022