Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force

Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force

Description

Molecular dynamics data files related to article Mykuliak et al. "Molecular dynamics simulations reveal how vinculin refolds partially unfolded talin rod helices to stabilize them against mechanical force" published in PLOS Computational Biology 2024
Show more

Year of publication

2024

Authors

Faculty of Medicine and Health Technology, Tampere University, Finland - Rights holder, Publisher

Vesa P. Hytönen Orcid -palvelun logo - Curator, Creator

Rolle Rahikainen - Contributor

Vasyl V. Mykuliak Orcid -palvelun logo - Creator

Scuola Internazionale Superiore di Studi Avanzati, SISSA, Italy

Giovanni Bussi - Contributor

University of Liverpool, UK

Benjamin T. Goult - Contributor

Neil J. Ball - Contributor

Other information

Fields of science

Biochemistry, cell and molecular biology

Open access

Open

License

Creative Commons Attribution 4.0 International (CC BY 4.0)

Keywords

Mechanobiology, Protein unfolding, Steered Molecular Dynamics, Mechanical load, Protein refolding