Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin

Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin

Description

Molecular dynamics data files related to article Mykuliak et al. "Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin" published in Plos Computational Biology 2018 https://doi.org/10.1371/journal.pcbi.1006126 File packages to download below: Explanation (271 bytes): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-9x201803202015018866347s Parameters for constant force SMD (12.26 kB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-10x201803212015017640010s Parameters for constant velocity SMD (12.26 kB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-3x201803212015018259029s Constant velocity SMD files for alpha-catenin (43.34 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-1x201803282015015731773s Constant velocity SMD files for talin R3 (6.9 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-2x201803282015017801656s Constant velocity SMD files for talin R9 (38.57 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-3x201803282015018275788s Constant velocity SMD files for disulphide-clamped talin R9 (24.75 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-1x201803202015015714588s Constant velocity SMD files for talin R9 tandems (57.52 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-10x201803202015017637286s Constant velocity SMD files for talin R11 (34.72 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-10x201803282015017670593s Constant force SMD files for talin R3 (9.0 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-9x201803202015018866341s Constant force SMD files for talin R9 (49.51 GB): http://avaa.tdata.fi/openida/dl.jsp?pid=urn:nbn:fi:csc-ida-4x201803202015018273068s
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Year of publication

2019

Authors

Lääketieteen ja biotieteiden tiedekunta - Publisher

Magdalena von Essen - Creator, Rights holder

Vasyl Mykuliak - Creator, Rights holder

Vesa Hytönen Orcid -palvelun logo - Creator, Rights holder, Curator

Other information

Fields of science

Biochemistry, cell and molecular biology

Language

No linguistic content

Open access

Restricted access

License

Creative Commons Attribution 4.0 International (CC BY 4.0)

Keywords

Molecular Dynamics, GROMACS, Mechanobiology, Protein unfolding, Steered Molecular Dynamics
Mechanical unfolding reveals stable 3-helix intermediates in talin and α-catenin - Research.fi