Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls"

< Back to search results

Data underlying the publication: "Lateral induction limits the impact of cell connectivity on Notch signaling in arterial walls"

Description

This study extends a previous 1D agent-based model for Notch signaling in arteries to a 2D formulation. This allows investigation of the effects of cell connectivity on the dynamics of arterial Notch signaling and VSMC phenotypes. Notch signaling for VSMCs with 2-6 neighbouring cells was analyzed. Computational results of the 1D and 2D formulations were also compared.
Show more

Year of publication

2020

Authors

4TU.ResearchData - Publisher

Eindhoven University of Technology

Sandra Loerakker - Creator

Tommaso Ristori - Creator

Åbo Akademi University

Cecilia Sahlgren Orcid -palvelun logo - Creator

Oscar Stassen - Creator

Other information

Fields of science

Biochemistry, cell and molecular biology

Open access

Open

License

Creative Commons Attribution 4.0 International (CC BY 4.0)

Keywords

Biomedical Engineering, FOS: Medical engineering, Notch signaling, agent-based model, growth and remodeling, artery, jagged, lateral induction, Time: 2020