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Mechanobiochemical finite element model to analyze impact‑loading‑induced cell damage, subsequent proteoglycan loss, and anti‑oxidative treatment effects in articular cartilage

Joonas Kosonen2025

Streamlined, single-step non-viral CRISPR-Cas9 knockout strategy enhances gene editing efficiency in primary human chondrocyte populations

Alexis Laurent, Angela Bonato, Goncalo Correia Pinto de Almeida Barreto, Lee Ann Applegate, Marcy Zenobi-Wong, Philipp Neidenbach, Simone Ponta, Valentino F. Bruhin2024

Injury-related cell death and proteoglycan loss in articular cartilage: Numerical model combining necrosis, reactive oxygen species, and inflammatory cytokines

Joonas Kosonen2022

A musculoskeletal finite element model of rat knee joint for evaluating cartilage biomechanics during gait

Gustavo Orozco2022

Mechanobiological model for simulation of injured cartilage degradation via pro-inflammatory cytokines and mechanical stimulus: experimental data, computational model results, and files to generate the models

Atte Eskelinen2020

Widespread regulation of gene expression by glucocorticoids in chondrocytes from patients with osteoarthritis as determined by RNA-Seq

Antti Pemmari, Eeva Moilanen, Katriina Vuolteenaho, Mari Hämäläinen, Teemu Moilanen, Tiina Leppänen2020