Optimization of boron neutron capture therapy (BNCT) for cancer treatment at Helsinki University Hospital accelerator-based BNCT facility

Description of the granted funding

Proton accelerator-based boron neutron capture therapy (BNCT) is a biologically targeted method to treat cancer. BNCT utilizes cancer-seeking boron carrier compounds and neutron irradiation to achieve very high radiation doses to tumors. BNCT may allow treating of otherwise difficult-to-treat cancers effectively. The first accelerator-based BNCT facility in Europe has been built on the Meilahti Academic Medicine Center campus, and it is the first facility in the world that is closely integrated with a large hospital radiation therapy department. This places Finland in the forefront in the development of BNCT. In this study, we aim to develop new tools for measuring accuracy of radiation dose delivery with BNCT to cancer, participate in research on novel boron carrier compounds, and initiate and conduct clinical trials to treat e.g. patients who face unfavorable survival outcomes with the currently available cancer treatments.
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Starting year

2023

End year

2027

Granted funding

Mikko Juhani Tenhunen Orcid -palvelun logo
437 960 €

Funder

Research Council of Finland

Funding instrument

Academy projects

Decision maker

Scientific Council for Natural Sciences and Engineering
06.06.2023

Other information

Funding decision number

355100

Fields of science

Physical sciences

Research fields

Fysiikka

Identified topics

cancer