EarlyAD project takes a groundbreaking approach for the research of Alzheimer’s disease (AD) by using idiopathic normal pressure hydrocephalus (iNPH) as a model for early stages of AD providing a rare chance to study AD before symptoms appear. The project utilizes brain biopsies, cerebrospinal fluid, blood and imaging data from iNPH and AD patients for the discovery of disease mechanisms and discovery of novel biomarkers related to immunometabolic alterations. Strong collaboration between the university and hospitals, expertise in advanced tissue function measurement techniques, genetics, and imaging technologies and integration of multi-level data with clinical information offer a unique opportunity to study disease mechanisms and identification of new biomarkers.

2025