The research focuses on uterine leiomyomas and endometrial polyps. These common tumors cause significant morbidity for women and major economic burden on societies. Occasionally, they may also transform into malignancy, leiomyomas to leiomyosarcomas and polyps to endometrial cancer. The aim of this project is to continue our long-term efforts to reveal the molecular background of uterine tumors. We aim to identify the genetic changes that lead to tumor development, to understand the tumorigenic mechanisms of the identified alterations, and to develop new clinically translatable tools that benefit diagnostics and improve patient management.

2025