Lymphatic vessels drain fluid from tissues back to the blood circulation and serve as a transport system for large molecules and immune cells. In recent years it has been found that lymphatic vessels are remarkably different in different organs, both in terms of their molecular identity, specialized biological functions and developmental origins. Our overarching hypothesis is that understanding the specific features, functions, and regulation of the diverse lymphatic vascular system is crucial for unraveling its roles in health and disease. Our goals include investigating how different organs communicate with lymphatic vessels, exploring mechanisms governing the growth of specific vessels, and identifying organ-specific progenitor cells involved in vessel development and regeneration. This exploration aims to provide comprehensive insights into the regulation and function of the lymphatic system, paving the way for targeted therapeutic interventions.

2025

2029