Improving the efficacy-safety balance of polypharmacology in multi-target drug discovery
Year of publication
2018
Authors
Ravikumar, Balaguru; Aittokallio, Tero
Organizations and authors
University of Turku
Aittokallio Tero
Publication type
Publication format
Article
Parent publication type
Journal
Article type
Review article
Audience
ScientificPeer-reviewed
Peer-ReviewedMINEDU's publication type classification code
A2 Review article, Literature review, Systematic reviewPublication channel information
Journal
Parent publication name
Volume
13
Issue
2
Pages
179-192
ISSN
Publication forum
Publication forum level
1
Open access
Open access in the publisher’s service
No
Self-archived
Yes
Other information
Fields of science
Mathematics; Pharmacy; Biomedicine
Keywords
CANCER-CELLS; computational methods; COMPUTATIONAL MODELS; data resources; DE-NOVO DESIGN; drug combination therapies; drug repositioning; efficacy-toxicity ratio; KINASE INHIBITOR; LIGAND-BINDING-SITES; multi-target drug design; Polypharmacology; profiling strategies; PROTEIN INVERSE DOCKING; screening libraries; SIDE-EFFECT TARGETS; SMALL-MOLECULE; TARGET INTERACTION NETWORKS; WEB SERVER; web-tools
Publication country
United Kingdom
Internationality of the publisher
International
Language
English
International co-publication
No
Co-publication with a company
No
DOI
10.1080/17460441.2018.1413089
The publication is included in the Ministry of Education and Culture’s Publication data collection
Yes