Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype
Year of publication
2025
Authors
Hellén, Marianna; Weert, Isabelle; Müller, Stephan A.; Räsänen, Noora; Kettunen, Pinja; Lehtonen, Sarka; Peitz, Michael; Fliessbach, Klaus; Takalo, Mari; Koskuvi, Marja; Lichtenthaler, Stefan F.; Leinonen, Ville; Ramirez, Alfredo; Karkkainen, Olli; Hiltunen, Mikko; Koistinaho, Jari; Rolova, Taisia
Show moreOrganizations and authors
University of Helsinki
Weert Isabelle
Koistinaho Jari
Hellén Marianna
Koskuvi Marja
Räsänen Noora
Kettunen Pinja
Lehtonen Sarka
Rolova Taisia
University of Eastern Finland
Lehtonen Sarka 
Kärkkäinen Olli Kalevi
Takalo Mari Anna
Hiltunen Mikko Juhani
Leinonen Ville
Publication type
Publication format
Article
Parent publication type
Journal
Article type
Original article
Audience
ScientificPeer-reviewed
Peer-ReviewedMINEDU's publication type classification code
A1 Journal article (refereed), original researchPublication channel information
Journal
Parent publication name
Volume
22
Issue
1
Article number
147
ISSN
Publication forum
Publication forum level
1
Open access
Open access in the publisher’s service
Yes
Open access of publication channel
Fully open publication channel
License of the publisher’s version
CC BY
Self-archived
No
Other information
Fields of science
Biomedicine; Neurosciences
Internationality of the publisher
International
Language
English
International co-publication
Yes
Co-publication with a company
No
DOI
10.1186/s12974-025-03470-y
The publication is included in the Ministry of Education and Culture’s Publication data collection
Yes