Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure–Activity Relationships, Antiviral Activity, and X-ray Structure Determination

Year of publication

2022

Authors

Pillaiyar, Thanigaimalai; Flury, Philipp; Krüger, Nadine; Su, Haixia; Schäkel, Laura; Barbosa Da Silva, Elany; Eppler, Olga; Kronenberger, Thales; Nie, Tianqing; Luedtke, Stephanie; Rocha, Cheila; Sylvester, Katharina; Petry, Marvin RI; McKerrow, James H; Poso, Antti; Pöhlmann, Stefan; Gütschow, Michael; O’Donoghue, Anthony J; Xu, Yechun; Müller, Christa E; Laufer, Stefan A

Organizations and authors

University of Eastern Finland

Poso Antti Tapani

Publication type

Publication format

Article

Parent publication type

Journal

Article type

Original article

Audience

Scientific

Peer-reviewed

Peer-Reviewed

MINEDU's publication type classification code

A1 Journal article (refereed), original research

Publication channel information

Journal/Series

Journal of medicinal chemistry

Volume

Issue

Pages

9376-9395

ISSN

0022-2623

Publication forum

61000

Publication forum level

Open access

Open access in the publisher’s service

Open access of publication channel

Partially open publication channel

Self-archived

Yes

Other information

Fields of science

Pharmacy

Internationality of the publisher

International

Language

English

International co-publication

Yes

Co-publication with a company

DOI

10.1021/acs.jmedchem.2c00636

The publication is included in the Ministry of Education and Culture’s Publication data collection

Yes