The project DISIMO deals with the digital detection of molecules using photonic detection. Array of metallic pads are functionalized with receptor probes and upconversion fluorescence is applied in the monitoring of molecule binding kinetics. Only one molecule-conjugate can be trapped on one pad enabling digital detection principle. Each pad of the platform array is nano-structured for a higher and localized excitation of the up-conversion centers. A dielectric mirror is enabling a directional emission of the up-converted signal for a higher detection. The technology can be used in diagnostics of communicable and non-communicable diseases, therapeutics and other domains, such as food quality and environmental monitoring.

2024

2028