Schizophrenia polygenic risk score and long-term success in the labour market : A cohort study
Year of publication
2022
Authors
Viinikainen, Jutta; Böckerman, Petri; Hakulinen, Christian; Kari, Jaana, T.; Lehtimäki, Terho; Raitakari, Olli, T.; Pehkonen, Jaakko
Abstract
Employment is rare among people with a schizophrenia diagnosis. Meanwhile, a genetic liability for schizophrenia may hinder labour market performance. We studied how the polygenic risk score (PGS) for schizophrenia related to education and labour market outcomes. We found that a higher PGS was linked to lower educational levels and weaker labour market outcomes as well as a higher likelihood of receiving social income transfers, particularly among men. Assuming that the link is causal, our results indicate that individuals with schizophrenia or schizophrenia-related traits have a weakened ability to fully participate in the labour market, potentially reinforcing social exclusion.
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Publication type
Publication format
Article
Parent publication type
Journal
Article type
Original article
Audience
ScientificPeer-reviewed
Peer-ReviewedMINEDU's publication type classification code
A1 Journal article (refereed), original researchPublication channel information
Journal/Series
Parent publication name
Volume
151
Pages
638-641
ISSN
Publication forum
Publication forum level
1
Open access
Open access in the publisher’s service
Yes
Open access of publication channel
Partially open publication channel
License of the publisher’s version
CC BY
Self-archived
Yes
Other information
Fields of science
Economics; Psychology; General medicine, internal medicine and other clinical medicine; Neurology and psychiatry; Public health care science, environmental and occupational health
Keywords
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Publication country
United Kingdom
Internationality of the publisher
International
Language
English
International co-publication
Yes
Co-publication with a company
Yes
DOI
10.1016/j.jpsychires.2022.05.041
The publication is included in the Ministry of Education and Culture’s Publication data collection
Yes